Effects of single nucleotide polymorphisms on human N-acetyltransferase 2 structure and dynamics by molecular dynamics simulation.
BACKGROUND: osborne hog feeders for sale Arylamine N-acetyltransferase 2 (NAT2) is an important catalytic enzyme that metabolizes the carcinogenic arylamines, hydrazine drugs and chemicals.This enzyme is highly polymorphic in different human populations.Several polymorphisms of NAT2, including the single amino acid substitutions R64Q, I114T, D122N,